Griffonia simplicifolia Lectin (GSL I) - Pure
Price: Regular price $250.00
Product Description
Griffonia simplicifolia lectin (GSL I) is affinity purified from a woody climbing shrub native to Africa. GSL I is composed of two types of subunits A and B that combine to form tetrameric structures, resulting in five isolectins. This lectin has affinity for terminal ?-D-galactosyl residues and terminal N-acetyl-?-D-galactosaminyl residues. The A-rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for ?-N-acetylgalactosamine residues, while the B-rich lectin preferentially agglutinates blood group B cells and is specific for ?-galactose residues. This lectin shows specificity for blood group B greater than blood group A1.
GSL I has been reported to bind several glycoproteins including laminin. Since some ?-D-galactosyl residues are expressed in endothelial cells of mouse tissues, GSL I can present a highly specific surface of glycosylation pattern in these cells.
Technical Specifications
| Abbreviation | : | GSL I |
| Material Source: | : | Bandeiraea |
| Conjugate: | : | None |
| Molecular Weight: | : | 114 kDa |
| Shelf Life: | : | 2 years |
| Blood Group Specificity: | : | B>A1 |
| Preferred Sugar Specificity: | : | α-Galactose, α-N-Acetylgalactosamine |
| Inhibiting or Eluting Sugar: | : | Galactose, N-Acetylgalactosamine |
| Divalent Ions: | : | Ca++, Mn++ |
| Mitogenic Activity: | : | No |
| Lyophilized or Liquid | : | Lyophilized |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
