Datura stramonium Lectin (DSA/DSL) - Semi-Pure
Price: Regular price $244.51
Product Description
Datura stramonium agglutinin or lectin (DSA/DSL) is purified by fractionation. Seeds of Datura stramonium contain at least three different carbohydrate-binding proteins, and the most prominent lectin is a dimeric glycoprotein composed of two nonidentical subunits that contains 40% carbohydrate. It binds well to N-acetylglucosamine, oligomers, and branched pentasaccharide, including two N-acetylglucosamine disaccharides linked to mannose (?-1,6) and (?-1,2), which is known to be the most potent inhibitor of agglutination. DSL prefers binding to (GlcNAc)2-4 and elutes with the sugar chitin hydrolysate. DSL binds well in the acidic pH range and its affinity decreases above pH 8.0. This agglutinin has blood group A, B, and O specificity. Studies have shown that DSA can act as a biomarker for neoplastic urotherial cells.
Technical Specifications
| Abbreviation | : | DSA/DSL |
| Material Source: | : | Jimson weed |
| Conjugate: | : | None |
| Appearance Form: | : | Powder |
| Preferred Sugar Specificity: | : | (N-Acetylglucosamine)2-4 |
| Inhibiting or Eluting Sugar: | : | Chitin Hydrolysate |
| Divalent Ions: | : | None Required |
| Mitogenic Activity: | : | Yes |
| Storage Temperature: | : | -20°C |
| Hazardous Shipping: | : | Non-hazardous |
