Maclura pomifera Lectin (MPL/MPA) - Semi-Pure
Price: Regular price $138.80
Product Description
Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Gal?1,3GalNAc?) and many O-linked glycopeptide structures. The structure of Gal?1,3GalNAc? occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins.
Technical Specifications
Abbreviation | : | MPL/MPA |
Material Source: | : | Osage orange |
Conjugate: | : | None |
Appearance Form: | : | Powder |
Preferred Sugar Specificity: | : | Galβ3GalNAc |
Inhibiting or Eluting Sugar: | : | Galactose |
Divalent Ions: | : | None Required |
Mitogenic Activity: | : | Yes |
Storage Temperature: | : | -20°C |
Hazardous Shipping: | : | Non-hazardous |