Morus alba Lectin (MLL) - Pure

Morus alba Lectin (MLL) - Pure

Price: Regular price $231.62

SKU#: 21511427-1

Product Description

The white mulberry, Morus alba L. is a source of many bioactive phytochemicals. Morus alba Lectin (MLL) is a 17kD glycoprotein with anti-proliferative properties. The mechanism of cell death induction by MLL on human breast cancer (MCF-7) and colon cancer (HCT-15) cells has been studied. Cells treated for 24 h with GI(50) concentration (concentration of lectin required for 50% inhibition of cell growth) of MLL (<10μg/ml for MCF-7 and 16 μg/ml for HCT-15)  induce cell death. MLL has sugar specificity for galactose and M-galactosamine glycans. MLL was affinity purified and tested to be pure protein which is highly glycosylated.

 

Technical Specifications

Abbreviation: MLL
Material Source:: White Mulberry Leaf
Conjugate:: None
Molecular Weight:: 17 kDa
Appearance Form:: Powder
Appearance Color:: White to off-white
Purity:: Affinity-purified
Shelf Life:: 2 years
Blood Group Specificity:: Rabbit erythrocytes
Preferred Sugar Specificity:: Galactose, N-Acetylgalactosamine
Inhibiting or Eluting Sugar:: Galactose
Divalent Ions:: None Required
Lyophilized or Liquid: Lyophilized
Storage Temperature:: -20ºC
Hazardous Shipping:: Non-hazardous

Applications

References

  • Khurtsidze, E., Kutchava, T., Pomikalova, N., & Gaidamashvili, M. (2017). Galactose-binding lectin from mulberry (Morus alba L.) seeds with growth hormone-like activity. Annals of Agrarian Science15(1), 26-30.
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