Morus alba Lectin (MLL) - Pure
Price: Regular price $231.62
Product Description
The white mulberry, Morus alba L. is a source of many bioactive phytochemicals. Morus alba Lectin (MLL) is a 17kD glycoprotein with anti-proliferative properties. The mechanism of cell death induction by MLL on human breast cancer (MCF-7) and colon cancer (HCT-15) cells has been studied. Cells treated for 24 h with GI(50) concentration (concentration of lectin required for 50% inhibition of cell growth) of MLL (<10μg/ml for MCF-7 and 16 μg/ml for HCT-15) induce cell death. MLL has sugar specificity for galactose and M-galactosamine glycans. MLL was affinity purified and tested to be pure protein which is highly glycosylated.
Technical Specifications
| Abbreviation | : | MLL |
| Material Source: | : | White Mulberry Leaf |
| Conjugate: | : | None |
| Molecular Weight: | : | 17 kDa |
| Appearance Form: | : | Powder |
| Appearance Color: | : | White to off-white |
| Purity: | : | Affinity-purified |
| Shelf Life: | : | 2 years |
| Blood Group Specificity: | : | Rabbit erythrocytes |
| Preferred Sugar Specificity: | : | Galactose, N-Acetylgalactosamine |
| Inhibiting or Eluting Sugar: | : | Galactose |
| Divalent Ions: | : | None Required |
| Lyophilized or Liquid | : | Lyophilized |
| Storage Temperature: | : | -20ºC |
| Hazardous Shipping: | : | Non-hazardous |
Applications
References
- Khurtsidze, E., Kutchava, T., Pomikalova, N., & Gaidamashvili, M. (2017). Galactose-binding lectin from mulberry (Morus alba L.) seeds with growth hormone-like activity. Annals of Agrarian Science, 15(1), 26-30.
